Channels, Receptors
and
Transporters

Cells and
Organelles

Tissues

Processes

Others

• TRP channels
• SERCA & PMCA
• Ca²⁺ channels
• Cl^- channels
• Transporters & Receptors

• Muscle
• Neurons
• Adipocytes
• Endothelial cells
• Epithelial cells
• Keratinocytes
• Photoreceptor
• Macrophages or lymphocytes
• Microglia
• Kidney
• Bone
• ER
• Mitochondria
• Gap junctions
• Cytoskeleton

• Hippocampus slices
• Uterus
• Vessels
• Myocardium

• Apoptosis
• Hypoxia & Ischemia
• Vision
• Pregnancy
• Nitric Oxide (NO)& Receptors
• Proliferation & cell cycle
• pH Control
• Cancer

• Miscellaneous

I. Channels, Receptors and Transporters

     A. TRP channels

Van Rossum DB, Patterson RL, Sharma S, Barrow RK, Kornberg M, Gill DL, Snyder SH., “Phospholipase Cgamma1 controls surface expression of TRPC3 through an intermolecular PH domain”Nature. 2005 Mar 3; 434(7029):99-104.

Gary St. J. Bird andJames W. Putney Jr., “Capacitative calcium entry supports calcium oscillations in human embryonic kidney cells” The Journal of Physiology Volume 562 Issue 3 Page 697 February 2005.

Mohamed Trebak, Gary St. J. Bird, Richard R. McKay, Lutz Birnbaumer, and James W. Putney Jr., “Signaling Mechanism for Receptor-activated Canonical Transient Receptor Potential 3 (TRPC3) Channels” Journal of  Biological Chemistry Vol. 278 Issue 18 16244-16252 May 2, 2003.

Jean-Philippe Lievremont, Gary S Bird, and James W Putney, Jr., “Canonical Transient Receptor Potential TRPC7 can function both as receptor-and store-operated channel in human embryonic kidney HEK293 cells” Am J Physiol Cell Physiol. 2004 Dec;287(6):C1709-16.

Kartik Venkatachalam, Hong-Tao Ma, Diana L. Ford, and Donald L. Gill, “Expression of Functional Receptor-coupled TRPC3 Channels in DT40 Triple Receptor InsP3 knockout Cells” Journal of Biological Chemistry Vol. 276 Issue 36 33980-33985 September 7, 2001.

Xiaoyan Wu, Tatiana K. Zagranichnaya, Grzegorz T. Gurda, Eva M. Eves, and Mitchel L. Villereal, “A TRPC1/TRPC3-mediated Increase in Store-operated Calcium Entry Is Required for Differentiation of H19-7 Hippocampal Neuronal Cells” Journal of Biological Chemistry  Vol. 279 Issue 42 43392-43402 October 15, 2004.

Kartik Venkatachalam, Fei Zheng and Donald L. Gill, “Regulation of Canonical Transient Receptor Potential (TRPC) Channel Function by Diacylglycerol and Protein Kinase C” Journal of Biological Chemistry Vol. 278 Issue 31 29031-29040 August 1, 2003.

Xiaoyan Wu, György Babnigg, Tatiana Zagranichnaya, and Mitchel L. Villereal, “The Role of Endogenous Human Trp4 in Regulating Carbachol-induced Calcium Oscillations in HEK-293 Cells” Journal of Biological Chemistry Vol. 277 Issue 16 13597-13608 April 19, 2002.

Li-Ping He, Thamara Hewavitharana, Jonathan Soboloff, Maria A. Spassova, and Donald L. Gill, “A Functional Link between Store-operated and TRPC Channels Revealed by the 3,5-Bis(trifluoromethyl)pyrazole Derivative, BTP2” Journal of Biological Chemistry Vol. 280 Issue 12 10997-11006 March 25, 2005.

Zakharov SI, Smani T, Dobrydneva Y, Monje F, Fichandler C, Blackmore PF, Bolotina VM., ”Diethylstilbestrol is a potent inhibitor of store-operated channels and capacitative Ca(2+) influx” Mol Pharmacol. 2004 Sep; 66(3):702-7.
Bolotina VM., “Store-operated channels: diversity and activation mechanisms” Sci STKE. 2004 Jul 20; 2004(243):pe34.
Gwanyanya A, Amuzescu B, Zakharov SI, Macianskiene R, Sipido KR, Bolotina VM, Vereecke J, Mubagwa K., ”Magnesium-inhibited, TRPM6/7-like channel in cardiac myocytes: permeation of divalent cations and pH-mediated regulation”  J Physiol. 2004 Sep 15; 559(Pt 3):761-76.

Smani T, Zakharov SI, Csutora P, Leno E, Trepakova ES, Bolotina VM., ”A novel mechanism for the store-operated calcium influx pathway” Nat Cell Biol. 2004 Feb;6(2):113-20. Epub 2004 Jan 18.

Smani T, Zakharov SI, Leno E, Csutora P, Trepakova ES, Bolotina VM., ”Ca2+-independent phospholipase A2 is a novel determinant of store-operated Ca2+ entry” J Biol Chem. 2003 Apr 4;278(14):11909-15.

Ming Yang, Anupma Gupta, Sergiy G. Shlykov, Rebecca Corrigan, Susan Tsujimoto and Barbara M. Sanborn, “Multiple Trp Isoforms Implicated in Capacitative Calcium Entry Are Expressed in Human Pregnant Myometrium and Myometrial Cells” Biology of Reproduction 67, 988-994 (2002).

Leissring, M.A.; Akbari, Y.; Fanger, C.M.; Chanalan, M.D.; Mattson, M.P.; La Ferla, F.M. “Capacitative Clacium Entry Deficits and Elevated Luminal Calcium Content in Mutant Presenilin-1 Knockin Mice.” Journal of Cell Biology 149(4) 793-797 (2000)

     B. SERCA & PMCA

     C. Ca2+ channels

Lee, H.C. “Modulator and messenger functions of cyclic ADP-ribose in calcium signaling”  Recent Progr Hormone Res 51:355-388 (1996).

Barger, SW.  “Complex influence of the L-type calcium-channel agonist BayK8644(+/-) on N-methyl-D-aspartate responses and neuronal survival.” Neuroscience 89(1):101-8 (1999)

Wang, X.S.; Gruenstein E. “Mechanism of Synchronized Calcium Oscillations in Cortical Neurons”  Brain Res. 767:239-249 (1997).

Phillippe, M.; Basa A. “Effects of Sodium and Calcium Channel Blockade on Cytosolic Calcium Oscillations and Phasic Contractions of Myometrial Tissue” J Soc Gynecol Invest, 4:72-77 (1997).

Ascher-Landsberg J; Saunders T; Elovitz M; Phillippe M.  “The effects of 2-aminoethoxydiphenyl borate, a novel inositol 1,4, 5-trisphosphate receptor modulator on myometrial contractions.” Biochem Biophys Res Commun 264(3):979-82 (1999).

Chien, E.K.; Saunders T; Phillippe M. “The mechanisms underlying Bay K 8644-stimulated phasic myometrial contractions” J. Soc Gynecol Invest 3:106-112 (1996).

Tang, Tianlai; Duffield, Rose; Ho, Andrew.  “Effects of Ca2+ channel blockers on Ca2+ loading induced by metabolic and hyperkalemia in cardiomyocytes.”  European Journel of Pharmacology 360(2-3):205-211 (1998).

Liu, LH; Paul, RJ; Sutliff, RL; Miller, ML; Lorenz, JN; Pun, RY; Duffy, JJ; Doetschman, T; Kimura, Y; MacLennan, DH; Hoying, JB; Shull, GE.  “Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3.” J Biol Chem 272(48):30538-45 (1997)

Chang, W; Pratt, SA; Chen, TH; Tu, CL; Mikala, G; Schwartz, A; Shoback, D.  “Parathyroid cells express dihydropyridine-sensitive cation currents and L-type calcium channel subunits.  Am J Physiol Endocrinol Metab. 2001 Jul;281(1):E180-9.

Li, W; Duncan, RL; Karin, NJ; Farach-Carson, MC.  “1,25 (OH)2D3 enhances PTH-induced Ca2+ transients in preosteoblasts by activating L-type Ca2+ channels.”  Am J Physiol. 1997 Sep;273(3 Pt 1):E599-605.

Li, W; Duncan, RL; Karin, NJ; Farach-Carson, MC.  “1,25 (OH)2D3 enhances PTH-induced Ca2+ transients in preosteoblasts by activating L-type Ca2+ channels.”  Am J Physiol. 1997 Sep;273(3 Pt 1):E599-605.

Aarhus, R.; Dickey DM; Graeff RM; Gee KR; Walseth TF; Lee HC. “Activation and inactivation of Ca2+ release by NAADP” J Biol Chem 271: 8513-8516 (1996).

Zhang, MI; O'Neil, RG.  “Molecular characterization of rabbit renal epithelial calcium channel.  Biochem Biophys Res Commun.” 2001 Jan 19;280(2):435-9.

György Babnigg, Tatiana Zagranichnaya, Xiaoyan Wu, and Mitchel L. Villereal, “Differential Tyrosine Phosphorylation of Plasma Membrane Ca2+-ATPase and Regulation of Calcium Pump Activity by Carbachol and Bradykinin” Journal of Biological Chemistry Vol. 278 Issue 17 14872-14882 April 25, 2003.

Brent J. F. Hill, Laxmansa C. Katwa, Brian R. Wamhoff and Michael Sturek, “Enhanced EndothelinA Receptor-Mediated Calcium Mobilization and Contraction in Organ Cultured Porcine Coronary Arteries”The Journal of Pharmacology and Experimental Therapeutics Vol. 295, Issue 2, 484-491, November 2000.

Theingi M. Thway, PhD; Sergiy G. Shlykov, PhD; Mary-Clare Day, BSN; Barbara M. Sanborn, PhD; Larry C. Gilstrap, III, MD; Yang Xia, MD, PhD; Rodney E. Kellems, PhD, “Antibodies From Preeclamptic Patients Stimulate Increased Intracellular Ca2+ Mobilization Through Angiotensin Receptor Activation” Circulation. 2004; 110:1612-1619.

Robert Aarhus, Deborah M. Dickey,  Richard M. Graeff,  Kyle R. Gee,  Timothy F. Walseth,  Hon Cheung Lee, “Activation and Inactivation of Ca Release by NAADP” The American Society for Biochemistry and Molecular Biology, Inc. Volume 271, Number 15, Issue of April 12, 1996 pp. 8513-8516.

Hon Cheung Lee, Robert Aarhus, Kyle R. Gee and Thomas Kestner, “Caged Nicotinic Acid Adenine Dinucleotide Phosphate SYNTHESIS AND USE” The American Society for Biochemistry and Molecular Biology, Inc. Volume 272, Number 7, Issue of February 14, 1997 pp. 4172-4178.

Hon Cheung Lee and Robert Aarhus, “Functional visualization of the separate but interacting calcium stores sensitive to NAADP and cyclic ADP-ribose” Journal of Cell Science 113, 4413-4420 (2000).

Patrick A. Singleton, Lilly Y.W. Bourguignon, “CD44 interaction with ankyrin and IPз receptor in lipid rafts promotes hyaluronan-mediated Ca²+ signaling leading to nitric oxide production and endothelial cell adhesion and proliferation” Experimental Cell Research 295 (2004) 102-118.

Wenhan Chang, Stacy A. Pratt, Tsui-Hua Chen, Chia-Ling Tu, Gabor Mikala, Arnold Schwartz, and Dolores Shoback, “Parathyroid cells express dihydropyridine-sensitive cation currents and L-type calcium channel subunits” Am J Physiol Endocrinol Metab Vol. 281, Issue 1, E180-E189, July 2001.

     D. Cl- channels

Matthias Froh, Ronald G. Thurman, and Michael D. Wheeler, “Molecular evidence for a glycine-gated chloride channel in macrophages and leukocytes” Am J Physiol Gastrointest Liver Physiol Vol. 283, Issue 4, G856-G863, October 2002.

Shunhei Yamashina, ­Akira Konno, ­Michael D. Wheeler, ­Ivan Rusyn, ­Elena V. Rusyn, ­Adrienne D. Cox, ­Ronald G. Thurman, “Endothelial Cells Contain a Glycine-Gated Chloride Channel”Nutrition and Cancer 2001, Vol. 40, No. 2, Pages 197-204.

Xiangli Li, Blair U. Bradford, Michael D. Wheeler, Stephen A. Stimpson, Heather M. Pink, Thomas A. Brodie, John H. Schwab, and Ronald G. Thurman, “Dietary Glycine Prevents Peptidoglycan Polysaccharide-Induced Reactive Arthritis in the Rat: Role for Glycine-Gated Chloride Channel” Infection and Immunity, September 2001, p. 5883-5891, Vol. 69, No. 9.

     E. Transporters & Receptors

Bird, IM; Sullivan, JA; Di, T; Cale, JM; Zhang, L; Zheng, J; Magness, RR.  “Pregnancy-dependent changes in cell signaling underlie changes in differential control of vasodilator production in uterine artery endothelial cells.”  Endocrinology. 2000 Mar;141(3):1107-17.

Holmberg, CI; Kukkonen, JP; Bischoff, A; Nasman, J; Courtney, MJ; Michel, MC; Akerman, KE. “Alpha2B-adrenoceptors couple to Ca2+ increase in both endogenous and recombinant expression systems.”  Eur J Pharmacol. 1998 Dec 11; 363(1):65-74.

Wang, X.S.; Ciraolo G; Morris R; Gruenstein E. “Identification of a Neuronal Endocytic Pathway Activated by an Apolipoprotein E Receptor Binding Peptide” Brain Res. 778:6-15 (1997).

Wang, X.S.; Gruenstein E.  “The Rapid Elevation of Neuronal Cytoplasmic Calcium by Apolipoprotein E Peptide”  J. Cell. Physiol. 173:73-83 (1997).

Kobayashi, S; Beitner-Johnson, D; Conforti, L; Millhorn, DE. “Chronic hypoxia reduces adenosine A2A receptor-mediated inhibition of calcium current in rat PC12 cells via down regulation of protein kinase A.” J Physiol (Lond) 512 (Pt 2):351-63 (1998)

Zhu, WH; Conforti, L; Millhorn, DE. “Expression of dopamine D2 receptor in PC-12 cells and regulation of membrane conductance by dopamine.” Am J Physiol 273(4 Pt 1):C1143-50 (1997).

Kobayashi, S.; Millhorn D.E. “Regulation of N-methyl-d-asparte receptor expression and n-methyl-d-aspartate-induced cellular response during chronic hypoxia in differentiated rat PC12 cells”. Neuroscience 101(4):1153-1162 (2000)

Phillippe, M.; Saunders T; Basa A. “Intracellular Mechanisms Underlying Prostaglandin F2a-Stimulated Phasic Myometrial Contractions.”  Am. J. Physiol. 273, (Endocrinol Metab 36) E:665-673 (1997).

Henkel, CC; Asbun, J; Ceballos, G; del Carmen, Castillo M; Castillo, EF. “Relationship between extra and intracellular sources of calcium and the contractile effect of thiopental in rat aorta.” Can J Physiol Pharmacol. 2001 May; 79(5):407-14.

Ho, AK; Duffield, R. “6-Hydroxydopamine-induced developmental cardiac alterations in morphology, calmodulin content, and K(2+)-mediated [Ca(2+)](i)Transient of chicken cardiomyocytes.” J Mol Cell Cardiol. 2000 Jul;32(7):1315-26.

Holmberg, CI; Kukkonen, JP; Bischoff, A; Nasman, J; Courtney, MJ; Michel, MC; Akerman, KE. “Alpha2B-adrenoceptors couple to Ca2+ increase in both endogenous and recombinant expression systems.”  Eur J Pharmacol. 1998 Dec 11;363(1):65-74.

Di T, Sullivan JA, Magness RR, Zhang L, Bird IM. “Pregnancy-Specific Enhancement of Agonist-Stimulated ERK-1/2 Signaling in Uterine Artery Endothelial Cells Increases Ca(2+) Sensitivity of Endothelial Nitric Oxide Synthase as well as Cytosolic Phospholipase A(2).” Endocrinology. 2001 Jul;142(7):3014-26.

Bird, IM; Sullivan, JA; Di, T; Cale, JM; Zhang, L; Zheng, J; Magness, RR.  “Pregnancy-dependent changes in cell signaling underlie changes in differential control of vasodilator production in uterine artery endothelial cells.”  Endocrinology. 2000 Mar;141(3):1107-17.

Kobayashi, S; Beitner-Johnson, D; Conforti, L; Millhorn, DE. “Chronic hypoxia reduces adenosine A2A receptor-mediated inhibition of calcium current in rat PC12 cells via downregulation of protein kinase A.” J Physiol (Lond) 512 ( Pt 2):351-63 (1998)

McNeil, L; Hobson, S; Nipper, V; Rodland, KD.  “Functional calcium-sensing receptor expression in ovarian surface epithelial cells.”  Am J Obstet Gynecol. 1998 Feb;178(2):305-13.

Di T, Sullivan JA, Magness RR, Zhang L, Bird IM. “Pregnancy-Specific Enhancement of Agonist-Stimulated ERK-1/2 Signaling in Uterine Artery Endothelial Cells Increases Ca(2+) Sensitivity of Endothelial Nitric Oxide Synthase as well as Cytosolic Phospholipase A(2).” Endocrinology. 2001 Jul;142(7):3014-26.

Torfs, H; Shariatmadari, R; Guerrero, F; Parmentier, M; Poels, J; Van Poyer, W; Swinnen, E; De Loof, A; Akerman, A; Vanden Broeck, J. “Characterization of a receptor for insect tachykinin-like peptide agonists by functional expression in a stable Drosophila Schneider 2 cell line.”J Neurochem. 2000 May;74(5):2182-9.

Akerman, Karl E.O.; Nasman, Johnny; Lund, Per-eric; Shariatmadari, Ramin; Kulkonen, Jykip.  “Endogenous extra cellular purine nucleotides redirect α2-adrenoceptor signaling.” FEBS Letters 430(3):209-212 (1998)

Aarhus, R.; Dickey DM; Graeff RM; Gee KR; Walseth TF; Lee HC. “Activation and inactivation of Ca2+ release by NAADP” J Biol Chem 271: 8513-8516 (1996).

Lee, H.C. “Modulator and messenger functions of cyclic ADP-ribose in calcium signaling”  Recent Progr Hormone Res 51:355-388 (1996).

McNeil, SE; Hobson, SA; Nipper, V; Rodland, KD.  “Functional calcium-sensing receptors in rat fibroblasts are required for activation of SRC kinase and mitogen-activated protein kinase in response to extracellular calcium.”  J Biol Chem. 1998 Jan 9;273(2):1114-20.

Ahn, JS; Camden, JM; Schrader, AM; Redman, RS; Turner, JT.  “Reversible regulation of P2Y(2) nucleotide receptor expression in the duct-ligated rat submandibular gland.”  Am J Physiol Cell Physiol. 2000 Aug;279(2):C286-94.

Attila Toth, Noemi Kedei, Yun Wang, Peter M. Blumberg, “Arachidonyl dopamine as a ligand for the vanilloid receptor VR1 of the rat” Life Sciences 73 (2003) 487-498.

José L. Boyer, Suzanne M. Delaney, Demetrio Villanueva, and T. Kendall Harden, “A Molecularly Identified P2Y Receptor Simultaneously Activates Phospholipase C and Inhibits Adenylyl Cyclase and Is Nonselectively Activated by All Nucleoside Triphosphates” Vol. 57, Issue 4, 805-810, April 2000.

Sarah M. Short, José L. Boyer, and R. L. Juliano, “Integrins Regulate the Linkage between Upstream and Downstream Events in G Protein-coupled Receptor Signaling to Mitogen-activated Protein Kinase” J Biol Chem, Vol. 275, Issue 17, 12970-12977, April 28, 2000

Charles Kennedy, Ai-Dong Qi, Christopher L. Herold, T. Kendall Harden, and Robert A. Nicholas, “ATP, an Agonist at the Rat P2Y4 Receptor, Is an Antagonist at the Human P2Y4 Receptor”Molecular Pharmacology Vol. 57, Issue 5, 926-931, May 2000.

Cheikh I. Seye, PhD; Qiongman Kong, BS; Laurie Erb, PhD; Richard C. Garrad, PhD; Brent Krugh, MS; Meifang Wang, MS; John T. Turner, PhD; Michael Sturek, PhD; Fernando A. González, PhD; Gary A. Weisman, PhD., “Functional P2Y2 Nucleotide Receptors Mediate Uridine 5'-Triphosphate–Induced Intimal Hyperplasia in Collared Rabbit Carotid Arteries” Circulation. 2002; 106:2720.

Brent J.F. Hill, Brian R. Wamhoff, and Michael Sturek, “Functional Nucleotide Receptor Expression and Sarcoplasmic Reticulum Morphology in Dedifferentiated Porcine Coronary Smooth Muscle Cells” Journal of Vascular Research 2001, 38: 432-443.

Chia-Ling Tu, Wenhan Chang, and Daniel D. Bikle,  “The Extracellular Calcium-sensing Receptor Is Required for Calcium-induced Differentiation in Human Keratinocytes” J. Biol. Chem., Vol. 276, Issue 44, 41079-41085, November 2, 2001.

Yun Wang, Noemi Kedei, Min Wang, Q. Jane Wang, Anna R. Huppler, Attila Toth, Richard Tran, and Peter M. Blumberg, “Interaction between Protein Kinase Cµ and the Vanilloid Receptor Type 1” J. Biol. Chem., Vol. 279, Issue 51, 53674-53682, December 17, 2004.

Yun Wang, Tamas Szabo, Jacqueline D. Welter, Attila Toth, Richard Tran, Jiyoun Lee, Sang Uk Kang, Young-Ger Suh, Peter M. Blumberg, and Jeewoo Lee, “High Affinity Antagonists of the Vanilloid Receptor” Molecular Pharmacology Vol. 62, Issue 4, 947-956, October 2002.

Yun Wang, Attila Toth, Richard Tran, Tamas Szabo, Jacqueline D. Welter, Peter M. Blumberg, Jiyoun Lee, Sang-Uk Kang, Ju-Ok Lim, and Jeewoo Lee, “High-Affinity Partial Agonists of the Vanilloid Receptor” Mol Pharmacol 64:325-333, 2003.

Ai-Dong Qi, Alexander C. Zambon, Paul A. Insel, and Robert A. Nicholas, “An Arginine/Glutamine Difference at the Juxtaposition of Transmembrane Domain 6 and the Third Extracellular Loop Contributes to the Markedly Different Nucleotide Selectivities of Human and Canine P2Y11 Receptors” Molecular Pharmacology Vol. 60, Issue 6, 1375-1382, December 2001.

Jae Suk Ahn, Jean M. Camden, Ann M. Schrader, Robert S. Redman, and John T. Turner, “Reversible regulation of P2Y2 nucleotide receptor expression in the duct-ligated rat submandibular gland”Am J Physiol Cell Physiol Vol. 279, Issue 2, C286-C294, August 2000.

Jin Qian, Melissa C. Colbert, David Witte, Chia-Yi Kuan, Eric Gruenstein, Hanna Osinska, Beate Lanske, Henry M. Kronenberg and Thomas L. Clemens, “Midgestational Lethality in Mice Lacking the Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Is Associated with Abrupt Cardiomyocyte Death” Endocrinology Vol. 144, No. 3 1053-1061 (2003).

I. Cells and Organelles

     A. Muscle

M. Seth, C. Sumbilla, S. P. Mullen, D. Lewis, M. G. Klein, A. Hussain, J. Soboloff, D. L. Gill and G. Inesi, ”Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) gene silencing and remodeling of the Ca2+ signaling mechanism in cardiac myocytes” PNAS |November 23, 2004 vol. 101 no. 47 16683-16688.

Jiaxuan Zhu, Ming Yu, Jill Friesema, Tianjian Huang, Richard J. Roman, and Julian H. Lombard, “Salt-induced ANG II suppression impairs the response of cerebral artery smooth muscle cells to prostacyclin” Am J Physiol Heart Circ Physiol 288: H908-H913, 2005.

Gwanyanya A, Amuzescu B, Zakharov SI, Macianskiene R, Sipido KR, Bolotina VM, Vereecke J, Mubagwa K., ”Magnesium-inhibited, TRPM6/7-like channel in cardiac myocytes: permeation of divalent cations and pH-mediated regulation”  J Physiol. 2004 Sep 15; 559(Pt 3):761-76.

Brent J.F. Hill, Brian R. Wamhoff, and Michael Sturek, “Functional Nucleotide Receptor Expression and Sarcoplasmic Reticulum Morphology in Dedifferentiated Porcine Coronary Smooth Muscle Cells” Journal of Vascular Research 2001, 38: 432-443.

Aslihan Aydemir-Koksoy, Joel Abramowitz, and Julius C. Allen, “Ouabain-induced Signaling and Vascular Smooth Muscle Cell Proliferation”J. Biol. Chem., Vol. 276, Issue 49, 46605-46611, December 7, 2001.

Douglas G. Johns, Zhaohui Ao, Diane Naselsky, Christopher L. Herold, Kristeen Maniscalco, Lea Sarov-Blat, Klaudia Steplewski, Nambi Aiyar and Stephen A. Douglas, “Urotensin-II-mediated cardiomyocyte hypertrophy: effect of receptor antagonism and role of inflammatory mediators” Naunyn-Schmiedeberg's Archives of Pharmacology Volume 370, Number 4, October 2004, Pages: 238 – 250.

Jin Qian, Melissa C. Colbert, David Witte, Chia-Yi Kuan, Eric Gruenstein, Hanna Osinska, Beate Lanske, Henry M. Kronenberg and Thomas L. Clemens, “Midgestational Lethality in Mice Lacking the Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Is Associated with Abrupt Cardiomyocyte Death” Endocrinology Vol. 144, No. 3 1053-1061 (2003).

Tang, Tianlai; Duffield, Rose; Ho, Andrew.  “Effects of Ca2+ channel blockers on Ca2+ loading induced by metabolic and hyperkalemia in cardiomyocytes.”  European Journel of Pharmacology 360(2-3):205-211 (1998).

Ho, AK; Duffield, R. “6-Hydroxydopamine-induced developmental cardiac alterations in morphology, calmodulin content, and K(2+)-mediated [Ca(2+)](i)Transient of chicken cardiomyocytes.” J Mol Cell Cardiol. 2000 Jul;32(7):1315-26.

     B. Neurons

Xiaoyan Wu, Tatiana K. Zagranichnaya, Grzegorz T. Gurda, Eva M. Eves, and Mitchel L. Villereal, “A TRPC1/TRPC3-mediated Increase in Store-operated Calcium Entry Is Required for Differentiation of H19-7 Hippocampal Neuronal Cells” Journal of Biological Chemistry  Vol. 279 Issue 42 43392-43402 October 15, 2004.

Shariatmadari, R; Lund, PE; Krijukova, E; Sperber, GO; Kukkonen, JP; Akerman, KE.  “Reconstitution of neurotransmission by determining communication between differentiated PC12 pheochromocytoma and HEL 92.1.7 erythroleukemia cells.”  Pflugers Arch. 2001 May; 442(2):312-20.

Barger, Steven W.; Basile, Anthony S. “Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function”. Journal of Neurochemistry 76 (3):846-845 (2001)

Barger, SW.  “Complex influence of the L-type calcium-channel agonist BayK8644(+/-) on N-methyl-D-aspartate responses and neuronal survival.” Neuroscience 89(1):101-8 (1999)

Moerman, AM; Barger, SW. “Inhibition of AMPA responses by mutated presenilin 1.” J Neurosci Res 57(6):962-7 (1999)

Wang, X.S.; Luebbe P; Gruenstein E; Zemlan F.  “Apolipoprotein E (ApoE) Peptide Regulates Tau Phosphorylation Via Two Different Signaling Pathways”  J. Neurosci. Res. (in press) (1998).

Wang, X.S.; Ciraolo G; Morris R; Gruenstein E. “Identification of a Neuronal Endocytic Pathway Activated by an Apolipoprotein E Receptor Binding Peptide” Brain Res. 778:6-15 (1997).

Wang, X.S.; Gruenstein E. “Mechanism of Synchronized Calcium Oscillations in Cortical Neurons”  Brain Res. 767:239-249 (1997).

Wang, X.S.; Gruenstein E.  “The Rapid Elevation of Neuronal Cytoplasmic Calcium by Apolipoprotein E Peptide”  J. Cell. Physiol. 173:73-83 (1997).

Talk, Andrew C.; Muzzio, Isabel A.; Matzel Louis D. “Neurophysiological substrates of context conditioning in Hermissenda suggest a temporally Invariant form of Activity-Dependent Neuronal Facilitation.” Neurobiology of Learning and Memory.72(2):95-117 (1999).

Kobayashi, S; Beitner-Johnson, D; Conforti, L; Millhorn, DE. “Chronic hypoxia reduces adenosine A2A receptor-mediated inhibition of calcium current in rat PC12 cells via down regulation of protein kinase A.” J Physiol (Lond) 512 (Pt 2):351-63 (1998)

Zhu, WH; Conforti, L; Millhorn, DE. “Expression of dopamine D2 receptor in PC-12 cells and regulation of membrane conductance by dopamine.” Am J Physiol 273(4 Pt 1):C1143-50 (1997).

Kobayashi, S.; Millhorn D.E. “Regulation of N-methyl-d-asparte receptor expression and n-methyl-d-aspartate-induced cellular response during chronic hypoxia in differentiated rat PC12 cells”. Neuroscience 101(4):1153-1162 (2000)

Kobayashi, S; Beitner-Johnson, D; Conforti, L; Millhorn, DE. “Chronic hypoxia reduces adenosine A2A receptor-mediated inhibition of calcium current in rat PC12 cells via downregulation of protein kinase A.” J Physiol (Lond) 512 ( Pt 2):351-63 (1998)

Cozzi D.E.P-G.A.; Peruginelli F.; Leonardi P.; Meli E.; Pellicciari R.; Moroni F., “1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia” European Journal of Neuroscience, October 1999, vol. 11, no. 10, pp. 3637-3647(11).

Carpenedo R.; Meli E.; Peruginelli F.; Pellegrini-Giampietro D.E.; Moroni F., “Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures” Journal of Neurochemistry, September 2002, vol. 82, no. 6, pp. 1465-1471(7).

Flavio Moroni, Sabina Attuci, Andrea Cozzi, Elena Meli, Roberta Picca, Mark A. Scheideler, Roberto Pellicciari, Christian Noe, Iran Sarichelou, Domenico E. Pellegrini-Giampietro, “The novel and systemically active metabotropic glutamate 1 (mGlu1) receptor antagonist 3-MATIDA reduces post-ischemic neuronal death” Neuropharmacology 42 (2002) 741-751.

     C. Adipocytes

Hang, Shi; Yuan-Di, Halvorsen; Ellis, Pamela N.; Wilkison, William O.; Zemel, Michael B.  “Role of Intracellular Calcium in human adipocyte differentiation.”  Physiological Genomincs 3: 75-82 (2000)

Hang Shi, Yuan-Di Halvorsen, Pamela N. Ellis, William O. Wilkison, and Michael B. Zemel, “Role of intracellular calcium in human adipocyte differentiation” Physiol. Genomics 3: 75-82, 2000.

     D. Endothelial cells

Bird, IM; Sullivan, JA; Di, T; Cale, JM; Zhang, L; Zheng, J; Magness, RR.  “Pregnancy-dependent changes in cell signaling underlie changes in differential control of vasodilator production in uterine artery endothelial cells.”  Endocrinology. 2000 Mar;141(3):1107-17.

Jian Wang, L. A. Shimoda, and J. T. Sylvester “Capacitative calcium entry and TRPC channel proteins are expressed in rat distal pulmonary arterial smooth muscle” Am J Physiol Lung Cell Mol Physiol 286: L848-L858, 2004.

Liu, LH; Paul, RJ; Sutliff, RL; Miller, ML; Lorenz, JN; Pun, RY; Duffy, JJ; Doetschman, T; Kimura, Y; MacLennan, DH; Hoying, JB; Shull, GE.  “Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3.” J Biol Chem 272(48):30538-45 (1997)

Bird, IM; Sullivan, JA; Di, T; Cale, JM; Zhang, L; Zheng, J; Magness, RR.  “Pregnancy-dependent changes in cell signaling underlie changes in differential control of vasodilator production in uterine artery endothelial cells.”  Endocrinology. 2000 Mar;141(3):1107-17.

Di T, Sullivan JA, Magness RR, Zhang L, Bird IM. “Pregnancy-Specific Enhancement of Agonist-Stimulated ERK-1/2 Signaling in Uterine Artery Endothelial Cells Increases Ca(2+) Sensitivity of Endothelial Nitric Oxide Synthase as well as Cytosolic Phospholipase A(2).” Endocrinology. 2001 Jul;142(7):3014-26.

Bird, IM; Sullivan, JA; Di, T; Cale, JM; Zhang, L; Zheng, J; Magness, RR.  “Pregnancy-dependent changes in cell signaling underlie changes in differential control of vasodilator production in uterine artery endothelial cells.”  Endocrinology. 2000 Mar;141(3):1107-17.

Di T, Sullivan JA, Magness RR, Zhang L, Bird IM. “Pregnancy-Specific Enhancement of Agonist-Stimulated ERK-1/2 Signaling in Uterine Artery Endothelial Cells Increases Ca(2+) Sensitivity of Endothelial Nitric Oxide Synthase as well as Cytosolic Phospholipase A(2).” Endocrinology. 2001 Jul;142(7):3014-26.

Shunhei Yamashina, ­Akira Konno, ­Michael D. Wheeler, ­Ivan Rusyn, ­Elena V. Rusyn, ­Adrienne D. Cox, ­Ronald G. Thurman, “Endothelial Cells Contain a Glycine-Gated Chloride Channel”Nutrition and Cancer 2001, Vol. 40, No. 2, Pages 197-204.

Ian M. Bird, Jeremy A. Sullivan, Tao Di, Jacqueline M. Cale, Lubo Zhang, Jing Zheng and Ronald R. Magness, “Pregnancy-Dependent Changes in Cell Signaling Underlie Changes in Differential Control of Vasodilator Production in Uterine Artery Endothelial Cells” Endocrinology Vol. 141, No. 3 1107-1117 (2000).

Tao Di, Jeremy A. Sullivan, Ronald R. Magness, Lubo Zhang and Ian M. Bird, “Pregnancy-Specific Enhancement of Agonist-Stimulated ERK-1/2 Signaling in Uterine Artery Endothelial Cells Increases Ca2+ Sensitivity of Endothelial Nitric Oxide Synthase as well as Cytosolic Phospholipase A2” Endocrinology Vol. 142, No. 7 3014-3026 (2001).

Alfredo Sierra-Ramirez, Tomas Morato, Rafael Campos, Ivan Rubio, Claudia Calzada, Enrique Mendez and Guillermo Ceballos, “Acute effects of testosterone on intracellular calcium kinetics in rat coronary endothelial cells are exerted through its aromatization to estrogens” Am. J. Physiol. Heart Circ. Physiol. (January 2004) 10.1152.

     E. Epithelial cells

 Nakamura S; “Glucose activates H+-ATPase in kidney epithelial cells”;

Am J Physiol Cell Physiol 287: C97-C105, 2004; doi :10.1152/ajpcell.         00469.2003   0363-6143/04

McNeil, L; Hobson, S; Nipper, V; Rodland, KD.  “Functional calcium-sensing receptor expression in ovarian surface epithelial cells.”  Am J Obstet Gynecol. 1998 Feb;178(2):305-13.

Zhang, MI; O'Neil, RG. “Kinetics of activation of a PKC-regulated epithelial calcium channel.” Cell Calcium. 2001 Apr;29(4):263-75.

Zhang, MI; O'Neil, RG.  “Molecular characterization of rabbit renal epithelial calcium channel.  Biochem Biophys Res Commun.” 2001 Jan 19;280(2):435-9.

Roland Lang, Peter I. Song, Franz J. Legat, Robert M. Lavker, Brad Harten, Henner Kalden, Eileen F. Grady, Nigel W. Bunnett, Cheryl A. Armstrong, and John C. Ansel, “Human Corneal Epithelial Cells Express Functional PAR-1 and PAR-2” Investigative Ophthalmology and Visual Science. 2003;44:99-105.

     F. Keratinocytes

Zhongjian Xie and Daniel D. Bikle, ”Phospholipase C-1 Is Required for Calcium-induced Keratinocyte Differentiation”  J Biol Chem, Vol. 274, Issue 29, 20421-20424, July 16, 1999.

Chia-Ling Tu, Wenhan Chang, and Daniel D. Bikle,  “The Extracellular Calcium-sensing Receptor Is Required for Calcium-induced Differentiation in Human Keratinocytes” J. Biol. Chem., Vol. 276, 

     G. Photoreceptor

Muzzio, IA; Talk, AC; Matzel, LD. “Intracellular Ca2+ and adaptation of voltage responses to light in Hermissenda photoreceptors.” Neuroreport 9(7):1625-31 (1998).

     H. Macrophages or lymphocytes

Robert F. Stachlewitz , Xiangli Li, Scott Smith, Hartwig Bunzendahl, Lee M. Gravesand, Ronald G. Thurman, “Glycine Inhibits Growth of T Lymphocytes by an IL-2-Independent Mechanism” The Journal of Immunology, 2000, 164: 176-182.

Matthias Froh, Ronald G. Thurman, and Michael D. Wheeler, “Molecular evidence for a glycine-gated chloride channel in macrophages and leukocytes” Am J Physiol Gastrointest Liver Physiol Vol. 283, Issue 4, G856-G863, October 2002.

Alberto Chiarugi, Maura Calvani, Elena Meli, Elisabetta Traggiai, Flavio Moroni, “Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages” Journal of Neuroimmunology 120 (2001) 190-198.

     I. Microglia

Barger, Steven W.; Basile, Anthony S. “Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function”. Journal of Neurochemistry 76 (3):846-845 (2001)

Steven W. Barger and Anthony S. Basile, “Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function” Journal of Neurochemistry Volume 76 Issue 3 Page 846 February 2001

     J. Kidney

Gary St. J. Bird andJames W. Putney Jr., “Capacitative calcium entry supports calcium oscillations in human embryonic kidney cells” The Journal of Physiology Volume 562 Issue 3 Page 697 February 2005.

Jean-Philippe Lievremont, Gary S Bird, and James W Putney, Jr., “Canonical Transient Receptor Potential TRPC7 can function both as receptor-and store-operated channel in human embryonic kidney HEK293 cells” Am J Physiol Cell Physiol. 2004 Dec;287(6):C1709-16.

Xiaoyan Wu, György Babnigg, Tatiana Zagranichnaya, and Mitchel L. Villereal, “The Role of Endogenous Human Trp4 in Regulating Carbachol-induced Calcium Oscillations in HEK-293 Cells” Journal of Biological Chemistry Vol. 277 Issue 16 13597-13608 April 19, 2002.

Pokorski, PL; McCabe, MJ Jr; Pounds, JG.  “Meso-2,3-dimercaptosuccinic acid induces calcium transients in cultured rhesus monkey kidney cells.”  Toxicology. 1999 Nov 5;138(2):81-91

     K. Bone

Chang, W; Pratt, SA; Chen, TH; Tu, CL; Mikala, G; Schwartz, A; Shoback, D.  “Parathyroid cells express dihydropyridine-sensitive cation currents and L-type calcium channel subunits.  Am J Physiol Endocrinol Metab. 2001 Jul;281(1):E180-9.

Li, W; Duncan, RL; Karin, NJ; Farach-Carson, MC.  “1,25 (OH)2D3 enhances PTH-induced Ca2+ transients in preosteoblasts by activating L-type Ca2+ channels.”  Am J Physiol. 1997 Sep;273(3 Pt 1):E599-605.

Chen, NX; Ryder, KD; Pavalko, FM; Turner, CH; Burr, DB; Qiu, J; Duncan, RL.  Ca(2+) regulates fluid shear-induced cytoskeletal reorganization and gene expression in osteoblasts. Am J Physiol Cell Physiol. 2000 May;278(5):C989-97.

Ryder, KD; Duncan, RL. “Parathyroid hormone modulates the response of osteoblast-like cells to mechanical stimulation.” Calcif Tissue Int. 2000 Sep;67(3):241-6.

Liu, R; Xu, Y; Farach-Carson, MC; Vogel, JJ; Karin, NJ.  “1,25 dihydroxyvitamin D(3) activates sphingomyelin turnover in ROS17/2.8 osteosarcoma cells without sphingolipid-induced changes in cytosolic Ca(2+).”  Biochem Biophys Res Commun. 2000 Jun 24;273(1):95-100.

Li, W; Duncan, RL; Karin, NJ; Farach-Carson, MC.  “1,25 (OH)2D3 enhances PTH-induced Ca2+ transients in preosteoblasts by activating L-type Ca2+ channels.”  Am J Physiol. 1997 Sep;273(3 Pt 1):E599-605.

Farah-Carson, Mary C. “Bioactive analogs that simulate subsets of biological activities of 1α,25(OH)2D3 in Osteoblasts.”  Steroids 66(3-5):357-361 (2001)

Camillo Peracchia, Anna Sotkis, Xiao G. Wang, Lillian L. Peracchia, and Anthony Persechini, “Calmodulin Directly Gates Gap Junction Channels” J. Biol. Chem., Vol. 275, Issue 34, 26220-26224, August 25, 2000.

     L. ER

     M. Mitochondria

David L. Maass, Jean White, Billy Sanders, and Jureta W. Horton, “Role of cytosolic vs. mitochondrial Ca2+ accumulation in burn injury-related myocardial inflammation and function” Am J Physiol Heart Circ Physiol 288: H744-H751, 2005.

     N. Gap junctions

Peracchia, C; Sotkis, A; Wang, XG; Peracchia, LL; Persechini, A.  “Calmodulin directly gates gap junction channels.”  J Biol Chem. 2000 Aug 25;275(34):26220-4.

Peracchia, C.; Wang XG; Li L; Peracchia LL. “Inhibition of calmodulin expression prevents low-pH-induced gap junction uncoupling in Xenopus oocytes” Pflugers Arch - Eru J Physiol, 431:479-487 (1996).

Wang, X. G.; Peracchia C. “Positive charges of the initial C-terminus domain of Cx32 inhibit gap junction gating sensitivity to CO2.”  Biophys. J 73:798-806 (1997).

     O. Cytoskeleton

III. Tissues

     A. Hippocampus slices

Ting Wang, MD; Kathleen M. Raley-Susman, PhD; Jun Wang, MD; Geoffrey Chambers, MS; James E. Cottrell, MD; Ira S. Kass, PhD, “Thiopental Attenuates Hypoxic Changes of Electrophysiology, Biochemistry, and Morphology in Rat Hippocampal Slice CA1 Pyramidal Cells” American Heart Association, Inc. (Stroke.1999;30:2400-2407.).

J. Wang, G. Chambers, J. E. Cottrell, and I. S. Kass, “Differential Fall in ATP Accounts for Effects of Temperature on Hypoxic Damage in Rat Hippocampal Slices” The Journal of NeurophysiologyVol. 83 No. 6 June 2000, pp. 3462-3472.

Carpenedo R.; Meli E.; Peruginelli F.; Pellegrini-Giampietro D.E.; Moroni F., “Kynurenine 3-mono-oxygenase inhibitors attenuate post-ischemic neuronal death in organotypic hippocampal slice cultures” Journal of Neurochemistry, September 2002, vol. 82, no. 6, pp. 1465-1471(7).

K. M. Raley-Susman, I. S. Kass, J. E. Cottrell, R. B. Newman, G. Chambers, and J. Wang, “Sodium Influx Blockade and Hypoxic Damage to CA1 Pyramidal Neurons in Rat Hippocampal Slices” The Journal of Neurophysiology Vol. 86 No. 6 December 2001, pp. 2715-2726

     B. Uterus

Phillippe, M. “Cellular mechanisms underlying magnesium sulfate inhibition of phasic myometrial contractions.” Biochem Biophys Res Commun 252(2):502-7 (1998)

Phillippe, M. ; Basa A. “(+) Cis-dioxolane stimulation of cytosolic calcium oscillations and phasic contractions of myometrial smooth muscle”  Biochem Biophys Res Comm 231:722-725 (1997).

Phillippe, M.; Basa A. “Effects of Sodium and Calcium Channel Blockade on Cytosolic Calcium Oscillations and Phasic Contractions of Myometrial Tissue” J Soc Gynecol Invest, 4:72-77 (1997).

Chien, E.K.; Saunders T; Phillippe M. “The mechanisms underlying Bay K 8644-stimulated phasic myometrial contractions” J. Soc Gynecol Invest 3:106-112 (1996).

Ascher-Landsberg J; Saunders T; Elovitz M; Phillippe M.  “The effects of 2-aminoethoxydiphenyl borate, a novel inositol 1,4, 5-trisphosphate receptor modulator on myometrial contractions.” Biochem Biophys Res Commun 264(3):979-82 (1999).

Phillippe, M.; Saunders T; Basa A. “Intracellular Mechanisms Underlying Prostaglandin F2a-Stimulated Phasic Myometrial Contractions.”  Am. J. Physiol. 273, (Endocrinol Metab 36) E:665-673 (1997).

Chien, E.K.; Saunders T; Phillippe M. “The mechanisms underlying Bay K 8644-stimulated phasic myometrial contractions” J. Soc Gynecol Invest 3:106-112 (1996).

Ascher-Landsberg, Jessica; Saunders, Trevania; Phillipe, Mark. “Tyrosine Kinase-mediated activation of cytosolic calcium oscillations and phasic myometrial contractions”. Journal of the society of Gynecologic Investigations 6(3):8240-244 (1999)

Bird, IM; Sullivan, JA; Di, T; Cale, JM; Zhang, L; Zheng, J; Magness, RR.  “Pregnancy-dependent changes in cell signaling underlie changes in differential control of vasodilator production in uterine artery endothelial cells.”  Endocrinology. 2000 Mar;141(3):1107-17.

     C. Vessels

Bingmei M. Fu and Shang Shen, “Structural Mechanisms of Acute VEGF Effect on Microvessel Permeability” Am J Physiol Hear Circ Physiol, January 30, 2003, 10.1152.

Brent J. F. Hill, Laxmansa C. Katwa, Brian R. Wamhoff and Michael Sturek, “Enhanced EndothelinA Receptor-Mediated Calcium Mobilization and Contraction in Organ Cultured Porcine Coronary Arteries”The Journal of Pharmacology and Experimental Therapeutics Vol. 295, Issue 2, 484-491, November 2000.

Cheikh I. Seye, PhD; Qiongman Kong, BS; Laurie Erb, PhD; Richard C. Garrad, PhD; Brent Krugh, MS; Meifang Wang, MS; John T. Turner, PhD; Michael Sturek, PhD; Fernando A. González, PhD; Gary A. Weisman, PhD., “Functional P2Y2 Nucleotide Receptors Mediate Uridine 5'-Triphosphate–Induced Intimal Hyperplasia in Collared Rabbit Carotid Arteries” Circulation. 2002; 106:2720.

Henkel, CC; Asbun, J; Ceballos, G; del Carmen, Castillo M; Castillo, EF. “Relationship between extra and intracellular sources of calcium and the contractile effect of thiopental in rat aorta.” Can J Physiol Pharmacol. 2001 May; 79(5):407-14.

Liu, LH; Paul, RJ; Sutliff, RL; Miller, ML; Lorenz, JN; Pun, RY; Duffy, JJ; Doetschman, T; Kimura, Y; MacLennan, DH; Hoying, JB; Shull, GE.  “Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3.” J Biol Chem 272(48):30538-45 (1997)

Bird, IM; Sullivan, JA; Di, T; Cale, JM; Zhang, L; Zheng, J; Magness, RR.  “Pregnancy-dependent changes in cell signaling underlie changes in differential control of vasodilator production in uterine artery endothelial cells.”  Endocrinology. 2000 Mar;141(3):1107-17.

Ian M. Bird, Jeremy A. Sullivan, Tao Di, Jacqueline M. Cale, Lubo Zhang, Jing Zheng and Ronald R. Magness, “Pregnancy-Dependent Changes in Cell Signaling Underlie Changes in Differential Control of Vasodilator Production in Uterine Artery Endothelial Cells” Endocrinology Vol. 141, No. 3 1107-1117 (2000).

Tao Di, Jeremy A. Sullivan, Ronald R. Magness, Lubo Zhang and Ian M. Bird, “Pregnancy-Specific Enhancement of Agonist-Stimulated ERK-1/2 Signaling in Uterine Artery Endothelial Cells Increases Ca2+ Sensitivity of Endothelial Nitric Oxide Synthase as well as Cytosolic Phospholipase A2” Endocrinology Vol. 142, No. 7 3014-3026 (2001).

Jiaxuan Zhu, Ming Yu, Jill Friesema, Tianjian Huang, Richard J. Roman, and Julian H. Lombard, “Salt-induced ANG II suppression impairs the response of cerebral artery smooth muscle cells to prostacyclin” Am J Physiol Heart Circ Physiol 288: H908-H913, 2005.

J. Asbun, B. Escalante, G. Ceballos, M.E. Ocharan, E.F. Castillo, and C. Castillo, “Clotrimazole Inhibits Nitric Oxide-Mediated-Relaxation Elicited by Acetylcholine in Rat Aortic Rings” Proc. West. Pharmacol. Soc. 41: 145-146, 1998.

Ming Yu, Ryan P. McAndrew, Rula Al-Saghir, Kris G. Maier, Meetha Medhora, Richard J. R. Roman, Elizabeth R. Jacobs, “Nitric Oxide Contributes to 20-HETE Induced Relaxation of Pulmonary Arteries” J. Appl. Physiol 2002, 10.1152.

Bingmei Fu and Shang Shen, “Acute VEGF effect on solute permeability of mammalian microvessels in vivo” Microvascular Research 68 (2004) 51-62.

Carlos Castillo Henkel, Juan Asbun, Guillermo Ceballos, María del Carmen Castillo, and Enrique F. Castillo, “Relationship between extra and intracellular sources of calcium and the contractile effect of thiopental in rat aorta” Can. J. Physiol. Pharmacol./Rev. Can. Physiol. Pharmacol. 79(5): 407-414 (2001).

John N. Lorenz and Eric Gruenstein, “A simple, nonradioactive method for evaluating single-nephron filtration rate using FITC-inulin” Am J Physiol Renal Physiol 276: F172-F177, 1999.

Kestrel M. Rogers, Christi A. Bonar, Jaymie L. Estrella, and Shumei Yang, “Inhibitory effect of glucocorticoid on coronary artery endothelial function” Am J Physiol Heart Circ Physiol Vol. 283, Issue 5, H1922-H1928, November 2002.

     D. Myocardium

Jureta W. Horton, D. Jean White, and David L. Maass, “Gender-related differences in myocardial inflammatory and contractile responses to major burn trauma” Am J Physiol Heart Circ Physiol 286: H202-H213, 2004.

Patricia J. Sikes, Piyu Zhao, David L. Maass, and Jureta W. Horton, “Time course of myocardial sodium accumulation after burn trauma: a 31P- and 23Na-NMR study” J Appl Physiol Vol. 91, Issue 6, 2695-2702, December 2001.